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Distinct Characteristics of Hodgkin's and Non-Hodgkin's Lymphoma

Matthew Taub

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Hematology physician Dr. Matthew Taub is board certified in medical oncology. A member of the Florida Medical Association and the American Society of Clinical Oncology, Dr. Matthew Taub treats various blood cancers, including Hodgkin’s lymphoma and Non-Hodgkin’s lymphoma.

Both lymphoma types originate in white blood cells called lymphocytes. Beyond this, many differences exist between the two immune system disorders.
Oncologists look for the presence of Reed-Sternberg cells during diagnosis. The visibility of these cells in an examination of cancer cells signals Hodgkin’s lymphoma.
Non-Hodgkin’s lymphoma is nearly nine times more prevalent than Hodgkin’s lymphoma. Non-Hodgkin’s lymphoma is more likely to occur in older patients, while Hodgkin’s lymphoma is found mostly in adolescents, young adults, and people over the age of 60.
Swollen lymph nodes are present in both lymphomas. In Hodgkin’s patients, swelling tends to cluster in the neck and upper body. With a survival rate of more than 90 percent, Hodgkin’s lymphoma is considered highly curable. As Non-Hodgkin’s lymphoma is often diagnosed in later stages, survival rates are slightly lower.